Pharmacy and Pharmaceutical Sciences: Recent submissions
Now showing items 41-60 of 622
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Prescription for Purposeful Adaptation of Professionalism-and-Ethics Teaching Strategies for Remote Delivery.
(2021)This case report outlines the strategies underpinning the adaptation of professionalism and ethics strand (P&E) teaching for remote delivery on a Pharmacy programme in response to COVID-19 restrictions. In line with national ... -
Deprescribing Falls Risk Increasing Drugs in Older Adults
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2023)Aim: The purpose of this thesis was to examine the facilitators of, and barriers to, implementing deprescribing of falls risk increasing medicines (FRIDs) in healthcare professionals' practices, by exploring the perspectives ... -
Deciphering the interplay of extracellular vesicles and drug resistance in HER2-positive breast cancer: insights, biomarkers and therapeutic implications
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2023)According to a World Health Organisation (WHO) report on 3rd March 2021, breast cancer is the most common form of cancer in the world and the leading cause of cancer death among females. In 2020, 2.26 million newly breast ... -
Approaches to Drying Hydrated Active Pharmaceutical Ingredients (APIs).
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2023)This project aims to develop a drying protocol that removes unwanted moisture from hydrated APIs while preserving water of hydration. Hydrate forms of model compounds, carbamazepine and theophylline, were generated with ... -
Milking extracellular vesicles for health benefit using a multi-omics approach
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2023)Milk is remarkable source of nutrients (i.e., proteins, fat, and sugars) and extracellular vesicles (EVs). EVs are tiny vesicles release by cells into all biofluids including milk. Milk EVs have been gathered huge attention ... -
Exploring Membrane Transporters in Lung Epithelial Cells: Drug-Transporter Interaction Analyses in Different In Vitro Models
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2023)Over the last decade, the incidence of lung-related diseases such as asthma and chronic obstructive pulmonary disease and their associated morbidity have continuously risen. A heterogeneity in treatment response to commonly ... -
Mechanochemical Synthesis and Physicochemical Characterisation of Multicomponent Phases Comprising Lidocaine and Dicarboxylic Acids
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2023)Tuning of physicochemical properties of multicomponent phases incorporating active pharmaceutical ingredients (APIs) with counterions or coformers is a challenge that opens up unlimited possibilities for expanding applications ... -
Improving appropriate polypharmacy in older people in primary care
Introduction People are living longer but not necessarily in better health. The ageing population coupled with the increasing prevalence of chronic conditions has resulted in many older people being prescribed polypharmacy ... -
Economic evaluation of a collaborative model of pharmaceutical care in an Irish hospital: cost-utility analysis [version 1; peer review: 2 approved]
(2023)Background: A complex, collaborative pharmaceutical care intervention including medication review and reconciliation demonstrated a statistically significant reduction in the prevalence of discharge medication error and ... -
Medication-Related Outcomes and Health Equity: Evidence for Pharmaceutical Care
(2023)Marginalised people experience diminished access to pharmaceutical care and worse medication-related outcomes than the general population. Health equity is a global priority. This article explores the key evidence of health ... -
Rating Scales to Measure Adverse Effects of Medications in People with Intellectual Disability: A Scoping Review
(2022)Purpose: Intellectual disability (ID) is a chronic neurodevelopmental condition characterised by limitations in intelligence and adaptive skills with an onset prior to the age of 18 years. People with ID have complex ... -
Enantioseparation and structural optimisation of b-lactams and stilbene analogues for the treatment of triple negative breast and chemoresistant colorectal cancers
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2023)Triple negative breast cancer (TNBC) is characterised by an extremely aggressive clinical phenotype and minimal expression of typical breast cancer receptors such as the estrogen, progesterone or HER2 receptors.1, 2 Patient ... -
Effect of Extraction Methods on Essential Oil Composition: A Case Study of Irish Bog Myrtle -Myrica gale L.
(2023)Myrica gale is an aromatic peatland shrub that has reported traditional use as an insect repellent. Different extraction methodologies were used in this study to isolate the essential oil of Myrica gale L., including ... -
A journey from ethnomedicine in rural Kenya to network pharmacology using a critical research approach
(Trinity College Dublin. School of Pharmacy & Pharma. Sciences. Discipline of Pharmacy, 2023)Background: Traditional medicine (TM) is widely practiced globally, with inter-country figures on usage ranging from 30 to 90%. Research on TM is conducted for a multiplicity of reasons, among them health care and ... -
FS-44: Nature-Inspired Epoxy Resins: PinoDGE
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In-Vitro Product Performance of Parenteral Drug Products: View of the USP Expert Panel
(2022)Performance testing of parenteral products represents a broad arena of product types, test equipment, and analytical challenges. This Stimuli article is one in a series of Stimuli articles on product performance testing ...
