Pharmacy and Pharmaceutical Sciences: Recent submissions
Now showing items 541-560 of 622
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Platelets increase survival of adenocarcinoma cells challenged with anticancer drugs: mechanisms and implications for chemoresistance.
(2012)BACKGROUND AND PURPOSE: Cancer cells grow without the restraints of feedback control mechanisms, leading to increased cancer cell survival. The treatment of cancer is often complicated by the lack of response to ... -
Ethnopharmacology in Ireland: an overview
(2014)The aim of this review was to extract information of the book Medicinal Plants in Folk Tradition: An Ethnobotany of Britain & Ireland published in 2004 by Allen and Hatfield, to give an overview of plants with medicinal ... -
Analysis of platelet function: role of microfluidics and nanodevices
(2011)Platelet aggregation is essential for vascular haemostasis and thrombosis. To improve the therapy of arterial thrombotic disorders and identify novel therapeutic targets it is imperative to study basic mechanisms of platelet ... -
Potential for alcohol and drug interactions in older adults: evidence from the Irish longitudinal study on ageing
(2014)Background Older adults are susceptible to adverse effects from the concomitant use of prescription medications and alcohol. This study estimates the prevalence of exposure to alcohol interactive (AI) medications and ... -
Adhesion characteristics and stability assessment of lectin-modified liposomes for site-specific drug delivery
(2008)Carbohydrate moieties of the cellular glycocalyx have been suggested to play an important role in biological recognition processes during pathologic conditions, such as inflammation and cancer. Herein, we describe ... -
Medicines use review pilot project
(Primary Care Group, Health Service Executive (HSE), 2012) -
Baseline study of Community Pharmacy Practice in Ireland - report
(Pharmaceutical Society of Ireland, 2011) -
Hospital Pharmacy in Ireland
(Pharmaceutical Society of Ireland, 2012) -
Non-Prescription Medicinal Products containing codeine: guidance for pharmacists on safe supply to patients
(Pharmaceutical Society of Ireland, 2010) -
Danggui to Angelica sinensis root: Lost in translation? Are potential benefits of a TCM lost to European women? A review
(2014)AbstractEthnopharmacological relevance Danggui (Chinese Angelica root; Dong quai; Angelica sinensis (Oliv.) Diels.) is a traditional Chinese herbal remedy with a long history of use in China, Korea and Japan. Even today ... -
Synthesis and antiproliferative action of a novel series of maprotiline analogues
(2014)The synthesis of a diverse library of compounds structurally related to maprotiline, a norepinephrine reuptake transporter (NET) selective antidepressant which has recently been identified as a novel in vitro antiproliferative ... -
Collaborative pharmaceutical care in an Irish hospital: uncontrolled before-after study
(2014)Background We investigated the benefits of the Collaborative Pharmaceutical Care in Tallaght Hospital (PACT) service versus standard ward-based clinical pharmacy in adult inpatients receiving acute medical care, particularly ... -
Formation and physicochemical properties of crystalline and amorphous salts with different stoichiometries formed between ciprofloxacin and succinic acid
(2013)Multi-ionisable compounds, such as dicarboxylic acids, offer the possibility of forming salts of drugs with multiple stoichiometries. Attempts to crystallise ciprofloxacin, a poorly water soluble, amphoteric ... -
Troglitazone attenuates TGF-β1-induced EMT in alveolar epithelial cells via a PPARγ-independent mechanism
(2012)Peroxisome proliferator activated receptor ? (PPAR?) agonists are effective antifibrotic agents in a number of tissues. Effects of these agents on epithelial-mesenchymal transition (EMT) of primary alveolar epithelial cells ... -
Steroid/mucokinetic hybrid nanoporous microparticles for pulmonary drug delivery
(2013)In a number of pulmonary diseases, patients may develop abnormally viscous mucus reducing drug efficacy. To increase budesonide diffusion within lung fluid, we developed nanoporous microparticles (NPMPs) composed of ... -
The verapamil transporter in human alveolar epithelial cells (A549) does not interact with β2-receptor agonists
(2014)Affinity of different organs for verapamil is highly variable and organ-specific. For example, the drug exhibits high levels of accumulation in lung tissues. A transporter recognising verapamil as substrate has previously ... -
Tumour vasculature targeting agents in hybrid/conjugate drugs.
(2013)Tumour vasculature targeting has been a very active area of cancer drug discovery over the last decade. Growth of solid tumours beyond a certain point requires a sufficient blood supply in order for them to develop and ...
