| dc.contributor.advisor | Dorman, Charles | |
| dc.contributor.author | Keane, Orla Mary | |
| dc.date.accessioned | 2019-07-25T13:30:44Z | |
| dc.date.available | 2019-07-25T13:30:44Z | |
| dc.date.issued | 2003 | |
| dc.identifier.citation | Orla Mary Keane, 'The control of DNA gyrase expression and its role in deletion formation in Salmonella enterica', [thesis], Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Microbiology, 2003, pp 270 | |
| dc.identifier.other | THESIS 7166 | |
| dc.description.abstract | Salmonella typhimurium strain CJD671 can undergo the deletion of a 5kb segment of
DNA from its large virulence plasmid. This results in a transcriptional fusion between the rlgA gene, encoding a putative site-specific resolvase, and the spvR virulence gene
regulator. The strong activity of the rlgA promoter results in the overexpression of a lacZ reporter gene in the spv locus. Deletions are selected for by lactose and only occur when the bacteria are grown at elevated osmolarity. | |
| dc.format | 1 volume | |
| dc.language.iso | en | |
| dc.publisher | Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Microbiology | |
| dc.relation.isversionof | http://stella.catalogue.tcd.ie/iii/encore/record/C__Rb12429708 | |
| dc.subject | Microbiology, Ph.D. | |
| dc.subject | Ph.D. Trinity College Dublin | |
| dc.title | The control of DNA gyrase expression and its role in deletion formation in Salmonella enterica | |
| dc.type | thesis | |
| dc.type.supercollection | thesis_dissertations | |
| dc.type.supercollection | refereed_publications | |
| dc.type.qualificationlevel | Doctoral | |
| dc.type.qualificationname | Doctor of Philosophy (Ph.D.) | |
| dc.rights.ecaccessrights | openAccess | |
| dc.format.extentpagination | pp 270 | |
| dc.description.note | TARA (Trinity's Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.ie | |
| dc.identifier.uri | http://hdl.handle.net/2262/88905 | |
