Show simple item record

dc.contributor.advisorWalsh, Patrick
dc.contributor.authorHoran, Rachel M.
dc.date.accessioned2019-11-06T16:12:18Z
dc.date.available2019-11-06T16:12:18Z
dc.date.issued2015
dc.identifier.citationRachel M. Horan, 'The role of novel IL-1 family members in Inflammatory Bowel Disease', [thesis], Trinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine, 2015, pp 176
dc.identifier.otherTHESIS 11255
dc.description.abstractInflammatory Bowel Disease (IBD) is characterized by an imbalance between effector and regulatory arms of intestinal immunity. Emerging evidence suggests that IL-1 family members play a critical role in the maintenance of gut homeostasis. In this study we have measured expression levels of the novel IL-1 family members, IL-36 and IL-37, in a paediatric IBD cohort. We subsequently used the DSS model of colitis to investigate the role of the IL-36R pathway in intestinal inflammation.
dc.format1 volume
dc.language.isoen
dc.publisherTrinity College (Dublin, Ireland). School of Medicine. Discipline of Clinical Medicine
dc.relation.isversionofhttp://stella.catalogue.tcd.ie/iii/encore/record/C__Rb16919901
dc.subjectClinical Medicine, Ph.D.
dc.subjectPh.D. Trinity College Dublin.
dc.titleThe role of novel IL-1 family members in Inflammatory Bowel Disease
dc.typethesis
dc.type.supercollectionthesis_dissertations
dc.type.supercollectionrefereed_publications
dc.type.qualificationlevelDoctoral
dc.type.qualificationnameDoctor of Philosophy (Ph.D.)
dc.rights.ecaccessrightsopenAccess
dc.format.extentpaginationpp 176
dc.description.noteTARA (Trinity’s Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.ie
dc.identifier.urihttp://hdl.handle.net/2262/90229


Files in this item

Thumbnail
Thumbnail

This item appears in the following Collection(s)

Show simple item record