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Complex evolutionary dynamics in simple genomes: the paradoxical survival of intracellular symbiotic bacteria

Toft, Christina (Trinity College (Dublin, Ireland). Department of Genetics, 2009)

Symbiosis is one of the ways in which nature has been able to generate biological innovation by fusing two organisms with different complexities. Because of these differing complexities, many problems for both organisms ...

The genetics of Mycobacterium bovis infection in Irish cattle

Richardson, Ian William (Trinity College (Dublin, Ireland). Department of Genetics, 2016)

Infection of livestock with Mycobacterium bovis, is the causing agent of bovine tuberculosis and is of major economic and health concern globally, with the cost of livestock loss estimated at €2 billion globally. In developed ...

Interpretation and improvement of the current genetic epidemiology methodology for schizophrenia

RAMMOS, ALEXANDROS (Trinity College Dublin. School of Genetics & Microbiology. Discipline of Genetics, 2018)

Recent technological advancements have allowed for the development of new methodologies in the investigation of the genetic epidemiology of schizophrenia. Two of the most prominent methods in that field are the Polygenic ...

Mind Bomb Regulates Cell Death during TNF Signaling by Suppressing RIPK1's Cytotoxic Potential

MARTIN, SEAMUS (2018)

Extracellular Neutrophil Proteases Are Efficient Regulators of IL-1, IL-33, and IL-36 Cytokine Activity but Poor Effectors of Microbial Killing

MARTIN, SEAMUS; LAVELLE, EDWARD (2018)

Identification of small-molecule elastase inhibitors as antagonists of IL-36 cytokine activation

MARTIN, SEAMUS (2018)

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

MARTIN, SEAMUS (2018)

Genetic analyses of thalamocortical axon guidance and subpallial development

Mitsogiannis, Manuela D. (Trinity College (Dublin, Ireland). Department of Genetics, 2016)

Normal brain functioning in mammals depends on the establishment of specific, finely-organised neural networks connecting distant regions during development. In particular, sensory stimuli processing is supported by ...

A new family of vertebrate-specific Polycombs encoded by the Lcor/Lcorl genes balance PRC2 subtype activities

Bracken, Adrian; BREAST-Predict; Irish Cancer Society (Trinity College Dublin. School of Genetics & Microbiology. Discipline of Genetics, 2018)

The Polycomb Repressive Complex 2 (PRC2) is composed of the core subunits SUZ12, EED, RBBP4/7 and EZH1/2, which together are responsible for all di- and tri- methylation of lysine 27 on Histone H3 (H3K27me2/3). In addition, ...

A Genomic Compendium of an Island: Documenting Continuity and Change across Irish Human Prehistory

CASSIDY, LARA (Trinity College Dublin. School of Genetics & Microbiology. Discipline of Genetics, 2018)

Abstract embargoed until 24/5/2023

The Multilayered Prehistory of Wild Aurochs and Domestic Cattle

Bradley, Daniel; European Research Council (ERC) (Trinity College Dublin. School of Genetics & Microbiology. Discipline of Genetics, 2018)

This thesis explores 122 ancient genomes of domestic cattle and wild aurochs to investigate past population events such as domestication and admixture. Population genomics of ancient taurine domestics from the ancient Near ...

The role of death receptors in ER stress and Inflamation

O'CONNOR, HAZEL (Trinity College Dublin. School of Genetics & Microbiology. Discipline of Genetics, 2018)

Cell death induced in response to ER stress, particularly in response to classical ER stress-inducing agents thapsigargin, brefeldin A and tunicamycin, has been shown to be dependent on the ER stress-dependent upregulation ...

Herding Ancient Domesticates: From Bones to Genomes

MULLIN, VICTORIA ELIZABETH (Trinity College Dublin. School of Genetics & Microbiology. Discipline of Genetics, 2018)

This thesis demonstrates the power of the analysis of ancient domesticate genomes of cattle and sheep in order to analyse past population dynamics of the two species. In total 113 whole genomes and 127 mitogenomes of wild ...

The N-terminal A domain of fibronectin-binding proteins A and B promotes adhesion of Staphylococcus aureus to elastin.

FOSTER, TIMOTHY (2004)

Increased virulence of a fibronectin-binding protein mutant of Staphylococcus aureus in a rat model of pneumonia

FOSTER, TIMOTHY (2002)

Multiple mechanisms for the activation of human platelet aggregation by Staphylococcus aureus: roles for the clumping factors CfA and ClfB, the serine-aspartate repeat protein SdrE and protein A

FOSTER, TIMOTHY (2002)

The elastin binding protein of Staphylococcus aureus (EbpS) is expressed at the cell surface as an integral membrane protein and not as a cell wall-associated protein.

FOSTER, TIMOTHY (2002)

Loss of clumping factor B fibrinogen binding activity by Staphylococcus aureus involves cessation of transcription, shedding and cleavage by metalloprotease

FOSTER, TIMOTHY (2001)

Identification of residues in the Staphylococcus aureus fibrinogen-binding MSCRAMM clumping factor A (ClfA) that are important for ligand binding.

FOSTER, TIMOTHY (2001)

Staphylococcus schleiferi subsp. schleiferi expresses a fibronectin-binding protein.

FOSTER, TIMOTHY (1999)

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School of Genetics & Microbiology: Recent submissions

Complex evolutionary dynamics in simple genomes: the paradoxical survival of intracellular symbiotic bacteria ﻿

The genetics of Mycobacterium bovis infection in Irish cattle ﻿

Interpretation and improvement of the current genetic epidemiology methodology for schizophrenia ﻿

Mind Bomb Regulates Cell Death during TNF Signaling by Suppressing RIPK1's Cytotoxic Potential ﻿

Extracellular Neutrophil Proteases Are Efficient Regulators of IL-1, IL-33, and IL-36 Cytokine Activity but Poor Effectors of Microbial Killing ﻿

Identification of small-molecule elastase inhibitors as antagonists of IL-36 cytokine activation ﻿

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 ﻿

Genetic analyses of thalamocortical axon guidance and subpallial development ﻿

A new family of vertebrate-specific Polycombs encoded by the Lcor/Lcorl genes balance PRC2 subtype activities ﻿

A Genomic Compendium of an Island: Documenting Continuity and Change across Irish Human Prehistory ﻿

The Multilayered Prehistory of Wild Aurochs and Domestic Cattle ﻿

The role of death receptors in ER stress and Inflamation ﻿

Herding Ancient Domesticates: From Bones to Genomes ﻿

The N-terminal A domain of fibronectin-binding proteins A and B promotes adhesion of Staphylococcus aureus to elastin. ﻿

Increased virulence of a fibronectin-binding protein mutant of Staphylococcus aureus in a rat model of pneumonia ﻿

Multiple mechanisms for the activation of human platelet aggregation by Staphylococcus aureus: roles for the clumping factors CfA and ClfB, the serine-aspartate repeat protein SdrE and protein A ﻿

The elastin binding protein of Staphylococcus aureus (EbpS) is expressed at the cell surface as an integral membrane protein and not as a cell wall-associated protein. ﻿

Loss of clumping factor B fibrinogen binding activity by Staphylococcus aureus involves cessation of transcription, shedding and cleavage by metalloprotease ﻿

Identification of residues in the Staphylococcus aureus fibrinogen-binding MSCRAMM clumping factor A (ClfA) that are important for ligand binding. ﻿

Staphylococcus schleiferi subsp. schleiferi expresses a fibronectin-binding protein. ﻿

Complex evolutionary dynamics in simple genomes: the paradoxical survival of intracellular symbiotic bacteria

The genetics of Mycobacterium bovis infection in Irish cattle

Interpretation and improvement of the current genetic epidemiology methodology for schizophrenia

Mind Bomb Regulates Cell Death during TNF Signaling by Suppressing RIPK1's Cytotoxic Potential

Extracellular Neutrophil Proteases Are Efficient Regulators of IL-1, IL-33, and IL-36 Cytokine Activity but Poor Effectors of Microbial Killing

Identification of small-molecule elastase inhibitors as antagonists of IL-36 cytokine activation

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018

Genetic analyses of thalamocortical axon guidance and subpallial development

A new family of vertebrate-specific Polycombs encoded by the Lcor/Lcorl genes balance PRC2 subtype activities

A Genomic Compendium of an Island: Documenting Continuity and Change across Irish Human Prehistory

The Multilayered Prehistory of Wild Aurochs and Domestic Cattle

The role of death receptors in ER stress and Inflamation

Herding Ancient Domesticates: From Bones to Genomes

The N-terminal A domain of fibronectin-binding proteins A and B promotes adhesion of Staphylococcus aureus to elastin.

Increased virulence of a fibronectin-binding protein mutant of Staphylococcus aureus in a rat model of pneumonia

Multiple mechanisms for the activation of human platelet aggregation by Staphylococcus aureus: roles for the clumping factors CfA and ClfB, the serine-aspartate repeat protein SdrE and protein A

The elastin binding protein of Staphylococcus aureus (EbpS) is expressed at the cell surface as an integral membrane protein and not as a cell wall-associated protein.

Loss of clumping factor B fibrinogen binding activity by Staphylococcus aureus involves cessation of transcription, shedding and cleavage by metalloprotease

Identification of residues in the Staphylococcus aureus fibrinogen-binding MSCRAMM clumping factor A (ClfA) that are important for ligand binding.

Staphylococcus schleiferi subsp. schleiferi expresses a fibronectin-binding protein.