Surgery: Recent submissions
Now showing items 161-180 of 185
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Common data items in seven European oesophagogastric cancer surgery registries: Towards a European Upper GI Cancer Audit (EURECCA Upper GI)
(2014)Aims Seven countries (Denmark, France, Ireland, the Netherlands, Poland, Sweden, United Kingdom) collaborated to initiate a EURECCA (European Registration of Cancer Care) Upper GI project. The aim of this study was to ... -
Extended pancreatectomy in pancreatic ductal adenocarcinoma: definition and consensus of the International Study Group for Pancreatic Surgery (ISGPS)
(2014)Background: Complete macroscopic tumor resection is one of the most relevant predictors of long-term survival in pancreatic ductal adenocarcinoma. Because locally advanced pancreatic tumors can involve adjacent organs, ... -
Mitochondrial mutagenesis correlates with the local inflammatory environment in arthritis
(2012)Background: To examine the association between mitochondrial mutagenesis and the proinflammatory microenvironment in patients with inflammatory arthritis. Methods: Fifty patients with inflammatory arthritis underwent ... -
Visceral adiposity, insulin resistance and cancer risk
(2011)Background: There is a well established link between obesity and cancer. Emerging research is characterising this relationship further and delineating the specific role of excess visceral adiposity, as opposed to simple ... -
Internal hernia following total gastrectomy with Roux-en-Y reconstruction.
(2011)Internal herniation is a well-described complication after a gastric bypass, particularly when performed laparoscopically, although it is rarely described following a total gastrectomy. A 55-year-old lady presented with ... -
Long-term activation of the pro-coagulant response after neoadjuvant chemoradiation and major cancer surgery.
(2010)Background: The association between cancer, major surgery and venous thromboembolism (VTE) is well established. Multimodal therapy is increasingly being used as standard treatment for localised gastrointestinal ... -
COX-Derived prostanoid pathways in gastrointestinal cancer development and progression: Novel targets for prevention and intervention
(Elsevier, 2012)Arachidonic acid metabolism through cyclooxygenase (COX) pathways leads to the generation of biologically active eicosanoids. Eicosanoid expression levels vary during development and progression of gastrointestinal (GI) ... -
Pro-inflammatory and tumour proliferative properties of excess visceral adipose tissue
(2011)Obesity has been associated with increased incidence and mortality of oesophageal and colorectal adenocarcinoma. Excess central adiposity may drive this association through an altered inflammatory milieu. Utilizing a unique ... -
Successful tumour necrosis factor (TNF) blocking therapy suppresses oxidative stress and hypoxiainduced mitochondrial mutagenesis in inflammatory arthritis
(2011)INTRODUCTION: To examine the effects of tumour necrosis factor (TNF) blocking therapy on the levels of early mitochondrial genome alterations and oxidative stress. METHODS: Eighteen inflammatory arthritis patients ... -
Cancer Cachexia:Mechanisms and Clinical Implications
(Hindawi, 2011)Cachexia is amultifactorial process of skeletal muscle and adipose tissue atrophy resulting in progressive weight loss. It is associated with poor quality of life, poor physical function, and poor prognosis in cancer ... -
Day care general anaesthesia for a child with bardet-biedl syndrome.
(2010)Bardet-Biedl syndrome is a very rare autosomal-recessive disorder with pan-systemic effects. The perioperative period may be hazardous for patients with this disorder. We describe the presenting features and management of ... -
Impact of a new electronic handover system in surgery
(2011)Changing patterns of workflow in the hospital setting have highlighted the need for improvements in effective and safe handover of patient details. Financial constraints mean that hospitals are under increasing pressure ... -
Midgut pain due to an intussuscepting terminal ileal lipoma: a case report.
(2010)ABSTRACT: INTRODUCTION: The occurrence of intussusception in adults is rare. The condition is found in 1 in 1300 abdominal operations and 1 in 100 patients operated for intestinal obstruction. The child to adult ratio is ... -
The value of double balloon enteroscopy in diagnosing blue rubber bleb naevus syndrome: a case report.
(BioMed Central, 2010)Blue rubber bleb naevus syndrome is a rare vascular disorder associated with multiple gastrointestinal haemangiomas that have the potential for life-threatening haemorrhage. These may be difficult to diagnose, and have ... -
Acute urinary retention in a young man secondary to colonic irrigation: a case report
(BioMed Central, 2009)Introduction Autonomic innervation of the bladder is complex and regulated by a hierarchy of mechanisms of the central nervous system. Any dysfunction in these regulatory mechanisms can lead to acute urinary retention. Case ... -
The role of prostacyclin synthase and thromboxane synthase signaling in the development and progression of cancer
(2010)Prostacyclin synthase and thromboxane synthase signaling via arachidonic acid metabolism affects a number of tumor cell survival pathways such as cell proliferation, apoptosis, tumor cell invasion and metastasis, and ... -
Management of synchronous adenocarcinoma of the esophago-gastric junction and ampulla of Vater: case report of a surgically challenging condition
(BioMed Central, 2009)We report herein a case of a synchronous presentation of an adenocarcinoma of esophagago-gastric junction type II and an ampullary tumor that was treated by combined Whipple's pancreaticoduodenectomy, total gastrectomy and ... -
An unusual presentation of Boerhaave Syndrome: a case report
(BioMed Central, 2009)We present a unique case of Boerhaave Syndrome that may highlight the spectrum of barotrauma from a Mallory-Weiss tear to full-thickness perforation. In this case, perforation only became evident following air insufflation ... -
Management of gastro-bronchial fistula complicating a subtotal esophagectomy: a case report
(BioMed Central, 2009)Background The development of a fistula between the tracheobronchial tree and the gastric conduit post esophagectomy is a rare and often fatal complication. Case presentation A 68 year old man underwent radical ... -
COX-2 protects against thrombosis of the retinal vasculature in a mouse model of proliferative retinopathy.
(Molecular Vision, 2006)Purpose: Cyclooxygenases (COX-1 and COX-2) and prostaglandins regulate angiogenesis in several settings, including cancer and ischemia. In the eye, both selective inhibitors of COX-2 and nonselective COX inhibitors are ...
