Surgery: Recent submissions
Now showing items 181-185 of 185
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Mechanisms controlling cell cycle arrest and induction of apoptosis after 12-lipoxygenase inhibition in prostate cancer cells.
(American Association for Cancer Research, 2002)Extensive studies have implicated the role of dietary fatty acids in prostatecancer progression. Platelet-type 12-Lipoxygenase (12-LOX) has beenshown to regulate growth, metastasis, and angiogenesis of prostate cancer. The ... -
Vascular endothelial growth factor (VEGF) upregulates BCL-2 and inhibits apoptosis in human and murine mammary adenocarcinoma cells
(2001)Tumour progression is regulated by the balance of proliferation and apoptosis in the tumour cell population. To date, the role of vascular endothelial growth factor (VEGF) in tumour growth has been attributed to the induction ... -
The role of endotoxin/lipopolysaccharide in surgically induced tumour growth in a murine model of metastatic disease
(Nature Publishing Group, 1999)Surgical removal of a primary tumour is often followed by rapid growth of previously dormant metastases. Endotoxin or lipopolysaccharide, a cell wall constituent of Gram-negative bacteria, is ubiquitously present in air ... -
Overexpression of platelet-type 12-lipoxygenase promotes tumor cell survival by enhancing alpha(v)beta(3) and alpha(v)beta(5) integrin expression.
(American Heart Association, 2003)Background? Pulmonary hypertension induced by chronic hypoxia is characterized by thickening of pulmonary artery walls, elevated pulmonary vascular resistance, and right-heart failure. Prostacyclin analogues reduce pulmonary ... -
General Practice Referral Letters 'Tell me what you want'
(2007)Background: Good quality referral letters are an essential part of good clinical care and act as the interface between healthcare professionals in Primary and Secondary care. The letters should have enough information to ...