Psychiatry: Recent submissions
Now showing items 161-180 of 438
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Investigation of putative candidate genes involved in the pathogenesis of Schizophrenia using a large Irish case-control sample
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Psychiatry, 2008)This research thesis involved a candidate gene search for schizophrenia in the Irish population. It sought to identify candidate genes based on positional and functional information contained in previously published material. ... -
The effect of catecholaminergic genes on executive functions : a behavioural and fMRI study
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Psychiatry, 2009)This thesis describes a study in two parts aimed at elucidating genetic links to executive functions and their neurological correlates. The catecholamines (in particular dopamine and noradrenaline) are known to be heavily ... -
Mental disorders in the community dwelling elderly
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Psychiatry, 2000)The elderly population is increasing both in numbers and as a proportion of the overall population. Mental disorders are common among the elderly. Most older people with mental disorders live in the community and attend ... -
Characterising schizophrenia candidate susceptibility genes using intermediate phenotypes
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Psychiatry, 2008)This thesis describes the use of intermediate phenotypes as a method for understanding, at a behavioural level, the functional significance of candidate susceptibility genes for schizophrenia. The historical context for ... -
A molecular genetic investigation of schizophrenia in an Irish study population
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Psychiatry, 2006)Schizophrenia (OMIM 181500) is a complex genetic disorder, which affects ~1% of the population, and typically presents in early adulthood with abnormalities of perception (psychosis), cognition, information processing and ... -
A candidate gene search for autism
(Trinity College (Dublin, Ireland). School of Medicine. Discipline of Psychiatry, 2006)This research involved a candidate gene search for autism in the Irish population. It sought to identify candidate genes based on information from linkage studies, reports of chromosomal abnormalities, animal studies and ... -
New data and an old puzzle: The negative association between schizophrenia and rheumatoid arthritis
(2015)Background: A long-standing epidemiological puzzle is the reduced rate of rheumatoid arthritis (RA) in those with schizophrenia (SZ) and vice versa. Traditional epidemiological approaches to determine if this negative ... -
MIR137HG risk variant rs1625579 genotype is related to corpus callosum volume in schizophrenia
(2015)Genome-wide association studies implicate the MIR137HG risk variant rs1625579 (MIR137HGrv) within the host gene for microRNA-137 as a potential regulator of schizophrenia susceptibility. We examined the influence of ... -
Hearing the Unheard: An Interdisciplinary, Mixed Methodology Study of Women's Experiences of Hearing Voices (Auditory Verbal Hallucinations).
(2015)This paper explores the experiences of women who "hear voices" (auditory verbal hallucinations). We begin by examining historical understandings of women hearing voices, showing these have been driven by androcentric ... -
Tailoring Cognitive Behavioral Therapy to Subtypes of Voice-Hearing.
(2015)Cognitive behavioral therapy (CBT) for voice-hearing (i.e., auditory verbal hallucinations; AVH) has, at best, small to moderate effects. One possible reason for this limited efficacy is that current CBT approaches tend ... -
Functional mental capacity, treatment as usual and time: Magnitude of change in secure hospital patients with major mental illness Psychiatry
(2015)BACKGROUND: Decision making ability can change with time, depending on mental or physical health. Little is known about the factors that determine this change and the relationship of capacity to time. As a pilot for ... -
Factors affecting length of stay in forensic hospital setting: Need for therapeutic security and course of admission
(2015)BACKGROUND: Patients admitted to a secure forensic hospital are at risk of a long hospital stay. Forensic hospital beds are a scarce and expensive resource and ability to identify the factors predicting length of stay ... -
The DUNDRUM Toolkit V1.0.30
(TARA, 2016) -
A genome-wide association study for genetic susceptibility to Mycobacterium bovis infection in dairy cattle identifies a susceptibility QTL on chromosome 23
(2016)Background: Bovine tuberculosis (bTB) infection in cattle is a significant economic concern in many countries, with annual costs to the UK and Irish governments of approximately �190 million and �63 million, respectively, ...
