School of Medicine: Recent submissions
Now showing items 381-400 of 3444
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Limited evidence exists on the effectiveness of education and training interventions on trial recruitment; a systematic review
(2019)Objective: The objective of this study was to examine the effectiveness of education and training interventions on recruitment to randomized and non-randomized trials. Study design and setting: A systematic review of ... -
Supportive relationships between patients and family caregivers in specialist palliative care: A qualitative study of barriers and facilitators
(2024)Objectives: Patients with advanced illness and their family caregivers can be mutually supportive. However, what facilitates and/or restricts supportive relationships between patients and family caregivers in palliative ... -
A Report on North South Experiences of Doctoral Training for Development in Africa
(2012)‘North-South Experiences of Doctoral Training for Development in Africa’ is a study of three models of partnership between Trinity College Dublin (TCD) and higher education institutes in six African countries. The goal of ... -
Mortality from esophagectomy for esophageal cancer across low, middle, and high-income countries: An international cohort study
(2021)Background: No evidence currently exists characterising global outcomes following major cancer surgery, including esophageal cancer. Therefore, this study aimed to characterise impact of high income countries (HIC) versus ... -
Local NO2 concentrations and asthma among over-50s in Ireland: a microdata analysis
(2020)Background: Links between air pollution and asthma are less well established for older adults than some younger groups. Nitrogen dioxide (NO2) concentrations are widely used as an indicator of transport-related air pollution, ... -
Challenging times: Delivering gene therapies and an opportunity for shared learning
(2021)As we embrace the era of precision medicine, gene therapies are the vanguard in the fight to cure rare diseases. While rare diseases are just that, rare, it is suggested that patients with rare diseases worldwide outnumber ... -
A randomised, double-blind, placebo-controlled, pilot trial of intravenous plasma purified alpha-1 antitrypsin for SARS-CoV-2-induced Acute Respiratory Distress Syndrome: a structured summary of a study protocol for a randomised, controlled trial
(2021)The primary objective is to demonstrate that, in patients with PCR-confirmed SARS-CoV-2 resulting in Acute Respiratory Distress Syndrome (ARDS), administration of 120mg/kg of body weight of intravenous Prolastin®(plasma-purified ... -
A randomized, double-blind, placebo-controlled trial of intravenous alpha-1 antitrypsin for ARDS secondary to COVID-19
(2022)Background: Patients with severe coronavirus disease 2019 (COVID-19) develop a febrile pro-inflammatory cytokinemia with accelerated progression to acute respiratory distress syndrome (ARDS). Here we report the results of ... -
Feasibility assessment of an 8-week attention-based training programme in the management of chronic spontaneous urticaria
(2021)Background: Prescribing error represent a significant source of preventable harm to patients. Prescribing errors at discharge, including omission of pre-admission medications (PAM), are particularly harmful as they ... -
The Effect of Semaglutide on Blood Pressure in Patients without Diabetes: A Systematic Review and Meta-Analysis
(MDPI AG, 2023)(1) Background: Recent advances in the pharmacological treatment of obesity with glucagon-like peptide-1 receptor agonists (GLP-1 RA) highlight the potential to target excess body weight to improve blood pressure (BP). ... -
An exploration of the professional identity of clinical academics using repertory grid technique
(2022)Background: Clinicians who divide their time between clinical work and research have contributed to some of the most fundamental breakthroughs in medicine in recent history, yet their role is not always well-understood ... -
Assessment of an electronic patient record system on discharge prescribing errors in a Tertiary University Hospital
(2021)Background: Prescribing error represent a significant source of preventable harm to patients. Prescribing errors at discharge, including omission of pre-admission medications (PAM), are particularly harmful as they frequently ... -
Supervision, Interprofessional Collaboration, and Patient Safety in Intensive Care Units during the COVID-19 Pandemic
(American Thoracic Society, 2021)Background: To meet coronavirus disease (COVID-19) demands in the spring of 2020, many intensive care (IC) units (ICUs) required help of redeployed personnel working outside their regular scope of practice, causing an ... -
Health data to support local communities
(Trinity College Dublin, 2024)The Robert Emmet Community Development Project (CDP) highlighted community concerns with health problems among residents of Oliver Bond House, work done to describe building issues, and difficulties in having these issues ... -
Early Satiety in Cancer: An Investigation into a Highly Impactful Orphan Symptom
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2024)Patients with cancer experience multiple symptoms throughout the different stages of cancer care. One common symptom related to nutritional intake is known as early satiety. This symptom has no agreed definition but has ... -
Early Immune Responses to Emerging and Enduring Respiratory Pathogens
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2024)For most of recent history, Tuberculosis (TB) has been the leading cause of death by an infective agent worldwide. Tuberculosis is caused by Mycobacterium tuberculosis (Mtb), which infects human lungs following respiratory ... -
Measurement Properties of �Wii Fit Free Jogging� Virtual Distance
(2014)Objective: The aim of this study was to examine the measurement properties of an outcome associated with the Nintendo(®) (Kyoto, Japan) game "Wii™ Fit Free Jogging" called virtual distance. Investigations into virtual ... -
Active video games as a form of exercise and the effect of gaming experience: a preliminary study in healthy young adults.
(2012)Objectives: To examine the energy expenditure and heart rate response while playing active video games, and the effect of gaming experience on energy expenditure. Design: Cross-sectional study. Participants and ... -
Physical Activity is Associated with Metabolic Health in Men Living with HIV.
(2018)Metabolic health is a cause for concern among those living with HIV, especially those on antiretroviral therapy. Physical activity (PA) is known to benefit metabolic health, however, few studies have objectively measured ...