School of Medicine: Recent submissions
Now showing items 401-420 of 3444
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A feasibility study of a physiotherapy-led motivational programme to increase physical activity and improve cardiometabolic risk in people with major mental illness.
(2018)People with major mental illness (MMI) such as schizophrenia, bi- polar disease and major depression have a reduced life expectancy [1–3]. This is predominantly due to natural causes [4–8], such as cardiovascular disease ... -
Were Frailty Identification Criteria Created Equal? A Comparative Case Study on Continuous Non-Invasively Collected Neurocardiovascular Signals during an Active Standing Test in the Irish Longitudinal Study on Ageing (TILDA)
(2024)Background: In this observational study, we compared continuous physiological signals during an active standing test in adults aged 50 years and over, characterised as frail by three different criteria, using data from ... -
The Potential of "Wii Fit Free Jogging" as an Exercise Test
(Games for Health Journal, 2014)Objective: The aim of this study was to investigate the potential use of "Wii Fit Free jogging" (Nintendo, Kyoto, Japan) as a tool to estimate aerobic fitness in healthy young adults. It was hypothesized that virtual ... -
Diverse Roles for the Extracellular Glycome of Extra-intestinal Pathogenic Escherichia coli in Serum Resistance and more
(Trinity College Dublin. School of Medicine. Discipline of Clinical Microbiology, 2023)Extra-intestinal pathogenic Escherichia coli (ExPEC) is a major cause of urinary tract infections, bacteraemia, and sepsis. This laboratory, among others, has previously shown that prototypic urosepsis strain CFT073 is ... -
Comparative analysis of frailty identification criteria on continuous non-invasive neurocardiovascular signals during an active stand test in The Irish Longitudinal Study on Ageing (TILDA)
(2023)Frailty is a distinctive health state related to acceleration of biological ageing in which multiple body systems disproportionately lose their in-built reserves. Older people living with frailty are at higher risk of ... -
The Lived Experience of Frailty: Beyond Classification and Towards a Holistic Understanding of Health
(2024)Purpose: Frailty is characterised by decreased physiological reserves and vulnerability to stressors. Although scales such as the Fried’s Frailty Phenotype (FP), Frailty Index (FI), and Clinical Frailty Scale (CFS) are ... -
Haemodynamic Parameters Underlying the Relationship Between Sarcopenia and Blood Pressure Recovery on Standing
(2023)Background: Sarcopenia, delayed blood pressure (BP) recovery following standing, and orthostatic hypotension (OH) pose significant clinical challenges associated with ageing. While prior studies have established a link ... -
Capsule endoscopy with artificial intelligence-assisted technology: Real-world usage of a validated AI model for capsule image review
(2023)Background and study aims Capsule endoscopy is a time-consuming procedure with a significance error rate. Artificial intelligence (AI) can potentially reduce reading time significantly by reducing the number of images ... -
Reporting of occupational exposures to blood and body fluids in the primary dental care setting in Scotland: an evaluation of current practice and attitudes
(2014)Objectives: To evaluate experience, practice and beliefs regarding occupational exposures to blood and oral fluids among a random sample of 300 dentists working in Scotland's NHS primary dental services. Method: A ... -
An Investigation into Helicobacter pylori Treatment Outcomes and Host Responses
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2023)Helicobacter pylori (H. pylori) is a helical, gram-negative, micro-aerophilic bacterium that infects approximately 50% of the world?s population. Although many of those infected will be asymptomatic, H. pylori increases ... -
Outcomes of a fatigue management intervention for people with post COVID-19 condition.
(2024)Objective Fatigue is identified as one of the most prevalent and persistent problems reported by people with post COVID-19 condition that negatively impacts on everyday living and resumption of pre-COVID-19 lifestyle. A ... -
A convergent parallel mixed methods study of the end-of-life care experiences of people with intellectual disability in Ireland: Lessons learned from IDS TILDA.
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2023)Palliative care is a vital intervention to relieve the suffering of people living with, and dying from, life-limiting conditions. However, people with an intellectual disability experience inequity in their access to, and ... -
The effect of surface compliance on overground running biomechanics. A systematic review and meta-analysis
(2023)The surface upon which running is performed has been suggested as a potential cause of many running-related injuries. It remains unclear, however, what effect surface compliance has on running biomechanics. This study ... -
Contralateral selectivity of upper limb motor pools via targeted stimulation of the cervical spinal cord.
(2023)Transcutaneous spinal cord stimulation (tSCS) at the cervical level may facilitate improved upper-limb function in those with incomplete tetraplegia. While clinical trials are ongoing, there is still much debate regarding ... -
The Impact and Influence of Sports Related Concussion and Cardiovascular Risk Factors on Brain and Heart Health across an Ageing Population
(Trinity College Dublin. School of Medicine. Discipline of Physiology, 2023)This study focused on the relationship between perceptual performance, brain health, and cardiovascular (CV) profiles in both recreational athletes and non-athletes, bridging the gap between sensory integration, cognitive ... -
Multimodal Analysis for Brain Network Fingerprints in Parkinson's Disease Patients
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2023)Parkinson's disease is a neurodegenerative disorder that causes structural and functional abnormalities in the central nervous system. The disease leads to the development of cardinal motor symptoms, including bradykinesia, ... -
Deep Learning for Neuroimaging: Advancing Brain-Based Biomarkers of Autism Spectrum Disorder
(Trinity College Dublin. School of Medicine. Discipline of Psychiatry, 2023)In the last decade, deep learning (DL) has revolutionised fields like speech and vision through artificial neural networks. Can DL similarly transform biological psychiatry and neuroimaging? This thesis explores that ... -
Metabolic syndrome accelerates epigenetic ageing in older adults: Findings from The Irish Longitudinal Study on Ageing (TILDA).
(2023)Metabolic syndrome (MetS) is a risk factor for the development of diabetes, cardiovascular disease, and all-cause mortality. It has an estimated prevalence of 40 % among older adults. Epigenetic clocks, which measure ... -
The role of intermediaries in connecting community-dwelling adults to local physical activity and exercise: a scoping review
(2023)Introduction/Purpose Physical inactivity has been declared a global pandemic by the World Health Organization. Methods to connect inactive individuals from healthcare settings to physical activity include brief interventions ... -
Cardiovascular risk and systemic inflammation in male professional rugby: a cross-sectional study
(2023)Objective To investigate cardiovascular risk factors’ prevalence and association with systemic inflammation in professional male rugby players (RP). Methods A cross-sectional investigation of 46 professional male RP ...
