Browsing Physiology (Theses and Dissertations) by Subject "astrocytes"
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The effects of clozapine and haloperidol on astrocyte function and morphology
(Trinity College Dublin. School of Medicine. Discipline of Physiology, 2019)Schizophrenia is a chronic debilitating psychiatric disorder affecting approximately 1% of the population worldwide. The disorder is characterised by positive symptoms, negative symptoms, and clinical deficits in cognition. ... -
Exercise has persistent effects on learning and memory throught the lifespan: Analysis of the underlying mechanisms
(Trinity College Dublin. School of Medicine. Discipline of Physiology, 2018)Ageing is a complex process associated with a decline in organism functions. Ageing affects several cellular and molecular brain mechanisms and is commonly associated with decline in brain function, such as cognition and ... -
Investigating the role of mechanosensitive channel Piezo1 in the CNS
(Trinity College Dublin. School of Medicine. Discipline of Physiology, 2019)All cells in the organism are able to sense changes in the mechanical properties of their environment, translating them into chemical intracellular signals through a process termed mechanotransduction, mostly via ...