School of Medicine: Recent submissions
Now showing items 41-60 of 3444
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Cardiovascular Health, Functional Disability, and Leisure Activities Profiles in Relation to Mental Aging
(2020)We investigated cardiovascular health, functional disability and leisure activities profiles independently and in relation to cognitive decline and dementia in high and low-medium income countries using data from the ... -
Connectome-based predictive modeling of cognitive reserve using task-based functional connectivity
(2022)Cognitive reserve supports cognitive function in the presence of pathology or atrophy. Functional neuroimaging may enable direct and accurate measurement of cognitive reserve which could have considerable clinical ... -
Tooth loss is associated with prevalent diabetes and incident diabetes in a longitudinal study of adults in Ireland.
(2024)Aim: The aim of this study was to explore the relationship between periodontal status, tooth loss and diabetes among community-dwelling adults aged 50 years and over in Ireland. Methods: From respondents who attended a ... -
The impact of loneliness on healthcare use in older people: evidence from a nationally representative cohort
(2020)Aim: Concerns around loneliness leading to increased healthcare use persist in spite of a mixed evidence base and lack of adjustment for key potential confounders. We investigated the associations among loneliness, health ... -
Association of Antidepressants With Recurrent, Injurious and Unexplained Falls is Not Explained by Reduced Gait Speed.
(2020)Objective: To examine if antidepressants at baseline are associated with falls and syncope over 4 years follow-up and if any observed associations are explained by baseline gait speed. Design: Longitudinal study (three ... -
Association between metabolic syndrome and risk of both prevalent and incident frailty in older adults: Findings from The Irish Longitudinal Study on Ageing (TILDA)
(2022)Metabolic syndrome (MetS) consists of the cluster of central obesity, insulin resistance, hypertension and atherogenic dyslipidaemia. It is a risk factor for cardiovascular disease, diabetes, and mortality. The prevalence ... -
Social factors may mediate the relationship between subjective age-related hearing loss and episodic memory
(2020)Objectives: To investigate whether the relationship between subjective age-related hearing loss (SARHL) and episodic memory functioning is mediated by measures of social functioning.Methods: Using data from 8,163 adults ... -
Psychosocial adversity and allostatic load burden in midlife and older ages.
(2021)Objective: To investigate the individual and cumulative impact of childhood and adulthood adversity on allostatic load (AL) burden. Method: Retrospective cross-sectional study design involving 4,165 participants from ... -
Personality and Wealth Accumulation Among Older Couples: Do Dispositional Characteristics Pay Dividends?
(2016)This paper explores whether the ‘Big 5’ personality characteristics: Emotional Stability, Extraversion, Conscientiousness, Agreeableness, and Openness to Experience, contribute to net household wealth accumulation among ... -
Vitamin D Status Is Not Associated With Orthostatic Hypotension in Older Adults.
(2019)There has been much interest in investigating vitamin D status with orthostatic hypotension. However, studies have been small, inconsistent, and with a lack of standardization. The aim of this study was to investigate the ... -
Life-course social class is associated with later-life diabetes prevalence in women: evidence from the Irish Longitudinal Study on Ageing
(Bristol University Press, 2020)This study aimed to investigate the independent and synergistic effects of childhood and adult social class, as well as the effect of social mobility, on type 2 diabetes (T2D) risk in later life. Cross-sectional data ... -
Sexual activity in the over 50s population in Ireland
(The Irish Longitudinal Study on Ageing, Trinity College Dublin, 2017)The majority of adults aged over 50 in Ireland are sexually active, with 59% reporting they had sex in the past 12 months. The majority of sexually active adults were sexually active once or twice a month (36% of sexually ... -
`Wish to die' is independently associated with cardiovascular mortality in later life. Data from TILDA
(2021)Background: There is an established bidirectional relationship between mental and heart health in later life but the link between wish to die (WTD) and cardiovascular mortality is less well‐defined. Methods: This is a ... -
Examining the impact of socio-economic position (SEP) across the life course on cognitive function and brain structure in healthy ageing.
(2023)This study explores the relationship of life-course intergenerational social mobility with cognitive function and brain structure in older adults using Diagonal Reference Models. Data from the Irish Longitudinal Study on ... -
Baseline Mobility is Not Associated with Decline in Cognitive Function in Healthy Community-Dwelling Older Adults: Findings From The Irish Longitudinal Study on Ageing (TILDA)
(2017)Objectives: Few studies examine the relationship between Timed Up-and-Go (TUG), a commonly used clinical test, and cognitive decline. This study examines whether TUG, usual gait speed (UGS), and dual-task gait speed ... -
What factors are associated with advance care planning in community-dwelling older people? Data from TILDA
(2022)Purpose: To assess advance care planning (ACP) in a large population-representative sample of older people. Methods: At Wave 4 of the Irish Longitudinal Study on Ageing, participants were asked: Have you made your ... -
Impact of Standing Speed on the Peripheral and Central Hemodynamic Response to Orthostasis: Evidence From the Irish Longitudinal Study on Ageing.
(2020)Assessment of the cerebrovascular and cardiovascular response to standing has prognostic value for a range of outcomes in the older adult population. Studies generally attempt to control for standing speed differences by ... -
Education is positively associated with macular pigment: The Irish Longitudinal Study on Ageing (TILDA)
(2012)Purpose: The three carotenoids lutein, zeaxanthin, and meso-zeaxanthin, are found at the macula and referred to as macular pigment (MP). This study was undertaken to investigate determinants of MP in a large randomly ... -
Impaired Stabilisation of Orthostatic Cerebral Oxygenation is Associated with Slower Gait Speed: Evidence from The Irish Longitudinal Study on Ageing.
(2021)Background: Cerebral autoregulation (CAR) systems maintain blood flow to the brain across a wide range of blood pressures. Deficits in CAR have been linked to gait speed (GS) but previous studies had small sample sizes ...
