School of Medicine: Recent submissions
Now showing items 621-640 of 3444
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Heart Rate Recovery Velocity in Cardiac Disease
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2022)Introduction Rate of recovery of heart rate between 10 and 20 seconds following orthostatic challenge (HRR10-20) is a risk factor for all-cause mortality. Furthermore, both cardiac rehabilitation and completeness of coronary ... -
Hungry for More: Measuring Metabolomic Responses in ANCA-Activated Monocytes
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2022)Immunometabolism examines the links between immune cell function and their metabolism. Advances in liquid chromatography mass spectrometry (LC-MS) technologies have uncovered unique insights into cellular metabolomics. ... -
Evaluation of an in-house six-well screening plate as a means of detecting phenotypic triazole resistance in St. James's Hospital, Dublin with emphasis on Aspergillus fumigatus
(Trinity College Dublin. School of Medicine. Discipline of Clinical Microbiology, 2022)Aspergillus fumigatus is a ubiquitous saprophytic mould fungus found in nature. This fungus is present in the air, in soil, in foliage in our food stock and on inanimate surfaces. For healthy individuals, A. fumigatus poses ... -
A Literature Review of Barriers and Opportunities Presented by Digitally Enhanced Practical Skill Teaching and Learning in Health Science Education
(2022)Introduction: An evidence gap exists identifying the challenges and opportunities presented by digitally enhanced practical skill teaching and learning in health science education. A literature review was carried out ... -
Exploring the Coordination of Care for People with Multiple Morbidities and their Support Networks using Social Network Analysis: A Research Protocol
(2016)Multimorbidity is the presence of two or more chronic conditions within one individual. Continuity of care and appropriate treatment decisions are essential for these individuals in order to avoid adverse outcomes and ... -
How to engage with stakeholders through qualitative research
(Health Service Executive, 2015)This article provides an overview of qualitative research, focusing on key methods and approaches that would be useful for conducting exploratory investigations into service delivery and organisation in health and ... -
How to match research designs to organisational issues in health and social care
(Health Service Executive, 2015)In an era of evidence-based healthcare, health and social care professionals are increasingly required to rely on robust evidence to inform their decision-making, not only regarding their clinical practice, but also ... -
How to apply social network analysis concepts in health and social care.
(Health Service Executive, 2015)In an era of evidence-based healthcare, health and social care professionals are increasingly required to rely on robust evidence to inform their decision-making, not only regarding their clinical practice, but also ... -
Exploring how multimorbidity care is managed for an older Irish patient population within clinician networks: Preliminary findings from an SNA survey
(2017)Studies focusing on managing care for people with multimorbidity show: – Health Service Utilisation: Long-term Use; Multiple Services at Same Time; Community Dwelling Ageing Cohort – Health Service Integration: Difficulty ... -
Exploring Sex-Related Differences in Microglia May Be a Game-Changer in Precision Medicine
(2022)One area of microglial biology that has been relatively neglected until recently is sex differences and this is in spite of the fact that sex is a risk factor in several diseases that are characterized by neuroinflammation ... -
"Home is wherever Hongkongers are": Narratives of emigration and exile by pro-democracy Hongkongers.
(2022)Hong Kong has seen a huge wave of emigration in recent months due to the ongoing regime repression in the city since the 2019 mass protests. As an indication, by September, 2021, 88,000 Hongkongers have submitted resettlement ... -
On the incorporation of universal human rights values into an "everyday" healthcare ethics: a spiritual perspective
(2021)Background: The Universal Declaration of Human Rights adopted in Geneva in December 1948 has been part of a key set of documents framing universal human rights values and informing ethical practices in many spheres. Legal ... -
Determinants of Physical Activity Engagement and Physical Activity Intervention Adherence in Individuals with Mild Cognitive Impairment: A Mixed Methods Study
(Trinity College Dublin. School of Medicine. CentreFor Medical Gerontology, 2022)The overarching aim of this thesis was to to identify the determinants of PA engagement and PA intervention adherence in individuals with MCI to expand on this under-researched topic and better inform PA promotion and ... -
Neuropsychological and Neuropsychiatric Endophenotypes in Amyotrophic Lateral Sclerosis
(Trinity College Dublin. School of Medicine. Discipline of Clinical Medicine, 2022)Amyotrophic Lateral Sclerosis (ALS) is a fatal neurodegenerative disease, characterized by progressive muscle weakness and death, usually within 3-5 years from symptom onset. ALS is now recognized to be a multi-system ... -
Pre-exposure prophylaxis (PrEP) to prevent HIV: a systematic review and meta-analysis of clinical effectiveness, safety, adherence and risk compensation in all populations.
(2022)Objective: To conduct a systematic review and meta-analysis of randomised controlled trials (RCTs) of the effectiveness and safety of oral pre-exposure prophylaxis (PrEP) to prevent HIV. Methods: Databases (PubMed, ... -
Cardiovascular signal entropy predicts all-cause mortality: evidence from The Irish Longitudinal Study on Ageing (TILDA)
(2022)In this study, the relationship between cardiovascular signal entropy and the risk of seven-year all-cause mortality was explored in a large sample of community-dwelling older adults from The Irish Longitudinal Study on ... -
Title: Understanding a Low Vitamin D State in the Context of COVID-19
(2022)While a low vitamin D state has been associated with an increased risk of infection by SARS-CoV-2 in addition to an increased severity of COVID-19 disease, a causal role is not yet established. Here, we review the evidence ... -
Variability and agreement of frailty measures and risk of falls, hospital admissions and mortality in TILDA
(2022)Little is known about the within-person variability of different frailty instruments, their agreement over time, and whether use of repeat assessments could improve the strength of associations with adverse health outcomes. ... -
Exercise-Based Dysphagia Rehabilitation for Adults with Oesophageal Cancer: a Systematic Review
(2022)Background: Dysphagia is prevalent in oesophageal cancer with significant clinical and psychosocial complications. The purpose of this study was i) to examine the impact of exercise-based dysphagia rehabilitation on clinical ... -
Tooth loss and cognitive decline in community dwelling older Irish adults: A cross-sectional cohort study
(2022)Objectives: To investigate whether tooth loss and related loss of occluding tooth pairs, were associated with cognitive decline in a group of community dwelling older men and women from Ireland. Methods: A group of 2508 ...