dc.contributor.advisor | Atkins, Gregory | |
dc.contributor.author | Quinn, Kathrina | |
dc.date.accessioned | 2019-05-01T15:27:05Z | |
dc.date.available | 2019-05-01T15:27:05Z | |
dc.date.issued | 2006 | |
dc.identifier.citation | Kathrina Quinn, 'Effect of intranasal administration of Semliki Forest virus recombinant particles expressing interferon-beta on the progression of experimental autoimmune encephalomyelitis', [thesis], Trinity College (Dublin, Ireland). Department of Microbiology, 2006, pp 313 | |
dc.identifier.other | THESIS 7983 | |
dc.description.abstract | Multiple sclerosis (MS) is an autoimmune demyelinating disease of the CNS,
characterized by the presence of sclerotic lesions throughout the brain. MS is thought to
be a CD4+ T helper 1 disease caused by the infiltration of autoaggressive T cells which
upregulate T helper-1 cytokines such as TNF-a and IFN-y. Much success has been
achieved in the treatment of Relapsing Remitting Multiple Sclerosis (RRMS). It is thought
that the antiproliferative activity of IFN-P may inhibit the expansion of the autoaggressive
T cells in MS, therefore limiting disease progression. | |
dc.format | 1 volume | |
dc.language.iso | en | |
dc.publisher | Trinity College (Dublin, Ireland). Department of Microbiology | |
dc.relation.isversionof | http://stella.catalogue.tcd.ie/iii/encore/record/C__Rb13031749 | |
dc.subject | Microbiology, Ph.D. | |
dc.subject | Ph.D. Trinity College Dublin | |
dc.title | Effect of intranasal administration of Semliki Forest virus recombinant particles expressing interferon-beta on the progression of experimental autoimmune encephalomyelitis | |
dc.type | thesis | |
dc.type.supercollection | thesis_dissertations | |
dc.type.supercollection | refereed_publications | |
dc.type.qualificationlevel | Doctoral | |
dc.type.qualificationname | Doctor of Philosophy (Ph.D.) | |
dc.rights.ecaccessrights | openAccess | |
dc.format.extentpagination | pp 313 | |
dc.description.note | TARA (Trinity's Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.ie | |
dc.identifier.uri | http://hdl.handle.net/2262/86591 | |