Effects of smoking and ageing on cardiovascular function
Citation:
Maeve Ann Barry, 'Effects of smoking and ageing on cardiovascular function', [thesis], Trinity College (Dublin, Ireland). Department of Physiology, 2004, pp 414Download Item:
Abstract:
Ageing and smoking have both been identified as important risk factors for
cardiovascular morbidity and mortality. The aim of these studies was to investigate the
effects of ageing and smoking on autonomic and endothelial function. Both factors have
been associated with oxidative stress. Consequently, the influence of moderate-dose
antioxidant supplementation on several autonomic and endothelial parameters was
examined. Methods used include the assessment of cardiovascular responses to sustained
isometric handgrip exercise, mental stress, cold pressor testing and reactive hyperaemia
and the analysis of plasma levels of thrombomodulin, von Willebrand Factor, C-reactive
protein, endothelin-1 and circulating endothelial cells.
Author: Barry, Maeve Ann
Advisor:
Bell, ChristopherPublisher:
Trinity College (Dublin, Ireland). Department of PhysiologyNote:
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Full text availableKeywords:
Physiology, Ph.D., Ph.D. Trinity College DublinMetadata
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