| dc.contributor.advisor | Campbell, Veronica | |
| dc.contributor.author | Boland, Barry | |
| dc.date.accessioned | 2019-05-14T14:45:50Z | |
| dc.date.available | 2019-05-14T14:45:50Z | |
| dc.date.issued | 2003 | |
| dc.identifier.citation | Barry Boland, 'An investigation into the effect of A beta on cultured cortical neurons', [thesis], Trinity College (Dublin, Ireland). Department of Physiology, 2003, pp 392 | |
| dc.identifier.other | THESIS 7144 | |
| dc.description.abstract | Accumulation of the endogenously produced beta-amyloid (Aβ) peptide in senile plaques is involved in the development of Alzheimer’s disease. This study reports on potential molecular mechanisms underlying the cell death induced by Aβ (1-40) (2 μM) on cultured primary cortical neurons. Particular attention was paid to the downstream effects of in Aβ-induced increase in [Ca 2+]i and on intracellular organelles that included the mitochondria, lysosomes and endoplasmic reticulum. | |
| dc.format | 1 volume | |
| dc.language.iso | en | |
| dc.publisher | Trinity College (Dublin, Ireland). Department of Physiology | |
| dc.relation.isversionof | http://stella.catalogue.tcd.ie/iii/encore/record/C__Rb12373542 | |
| dc.subject | Physiology, Ph.D. | |
| dc.subject | Ph.D. Trinity College Dublin | |
| dc.title | An investigation into the effect of A beta on cultured cortical neurons | |
| dc.type | thesis | |
| dc.type.supercollection | thesis_dissertations | |
| dc.type.supercollection | refereed_publications | |
| dc.type.qualificationlevel | Doctoral | |
| dc.type.qualificationname | Doctor of Philosophy (Ph.D.) | |
| dc.rights.ecaccessrights | openAccess | |
| dc.format.extentpagination | pp 392 | |
| dc.description.note | TARA (Trinity's Access to Research Archive) has a robust takedown policy. Please contact us if you have any concerns: rssadmin@tcd.ie | |
| dc.identifier.uri | http://hdl.handle.net/2262/86777 | |
